Dr. Raphael Bueno

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Dr. Raphael Bueno

Chief of Division of Thoracic Surgery; Vice Chair of Surgery for Cancer and Translational Research

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Dr. Raphael Bueno is the Chief, Division of Thoracic Surgery and Vice Chair of Surgery for Cancer and Translational Research at Boston’s Brigham and Women’s Hospital, a teaching affiliate of the Harvard University College of Medicine where Dr. Bueno also serves as Professor of Surgery. As a 1985 graduate of Harvard Medical School, Dr. Bueno completed a residency program at Brigham and Women’s Hospital and a fellowship in Thoracic Surgery at the Massachusetts General Hospital.
Board certified in 1993, Dr. Bueno spent much of his early career teaching at the Harvard Medical College throughout the 1990’s. Much of Dr. Bueno’s more recent focus has been treating patients of malignant mesotheliomaand lung cancer at various stages. Dr. Bueno has studied extensively the behavior of all types of mesothelioma (including peritoneal mesothelioma and pericardial mesothelioma) at a cellular level with hopes of integrating his growing knowledge of cell-level behavior into more aggressive and effective mesothelioma treatment regimens.


Dr. Bueno’s current research initiatives include the investigation of new targets for lung cancer and mesothelioma therapies, as well as the development of tests aimed at detecting cancer and identifying the prognosis of patients with thoracic malignancies following surgery. He is the lead investigator of several ongoing clinical trials, one of which is examining biomarker responses in tumor tissue in surgical patients with malignant pleural mesothelioma.
Dr. Bueno serves today as Program and Research Director of the International Mesothelioma Program (IMP) at Brigham and Women’s Hospital/Harvard Medical School—the largest program of its kind in the world that was founded with the mission of offering patients with malignant pleural mesothelioma the most innovative and advanced treatment regimens available. Much of Dr. Bueno’s research has been published in national medical journals, including the Journal of Thoracic Cardiovascular Surgery. Among the topics explored in his publications are the molecular pathways and therapeutic targets in lung cancer, chemotherapeutic drug resistance in primary malignant pleural mesothelioma, and gene expression ratio testing targeting the classification of normal lung vs. lung tumors. U.S. News and World Report has recently lauded Dr. Bueno’s research in their physician rankings. Patients with malignant mesothelioma are urged to explore if Dr. Bueno’s expertise in the field may be beneficial to them.

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